Stains happen – let Purex 4-in-1 Advanced Oxi Plus Coldwater Power help with the clean-up. Our most powerful stain fighter* is formulated be tough on stains even in cold water and gives a boost of freshness. Put simply, Purex 4-in-1 Advanced Oxi Plus Coldwater Power provides a dependable clean at an affordable price. Purex laundry detergent is safe for all washing machines including High Efficiency (HE). *vs. regular Purex