Similac Pro-Total Comfort is the first gentle formula with partially hydrolyzed protein and 2'-FL HMO, an immune-nourishing prebiotic like that found in breast milk. Parents reported (After switching to Similac Pro-Total Comfort) a significant reduction in fussiness, gassiness, and crying after just 1 day, and the improvement was maintained. Our exclusive blend of DHA, Lutein, and Vitamin E is important for helping support baby's brain and eye development. You can trust Similac, the No. 1 infant formula brand chosen by moms (No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.) and the No. 1 brand fed in hospitals. (No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.).